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New 8x Fuel Injectors For 2004-2010 Chevy GMC 4.8 5.3 6.0 6.2 12580681

New 8x Fuel Injectors For 2004-2010 Chevy GMC 4.8 5.3 6.0 6.2 12580681 is a complete set of OEM-replacement fuel injectors priced at $43.95. Designed for V8 engines, it ensures optimal fuel delivery and engine performance for Chevrolet and GMC trucks and SUVs from 2004–2010.

$43.95

● In stock

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Price and availability may change. Click to see current details on Lab Work Auto.

Key features

  • OEM-replacement 12580681 specification
  • Complete set of 8 fuel injectors
  • Fits 4.8L, 5.3L, 6.0L, 6.2L V8 engines
  • Direct fit for 2004-2010 GM trucks and SUVs
  • Restores engine performance and fuel economy
  • No programming or calibration required
  • Affordable $43.95 price point

Pros

  • +Full set at low cost
  • +Exact OEM fitment
  • +Improves engine smoothness
  • +Easy installation
  • +Wide vehicle compatibility
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Cons

  • Not for high-horsepower builds
  • No flow testing data provided

About New 8x Fuel Injectors For 2004-2010 Chevy GMC 4.8 5.3 6.0 6.2 12580681

What is New 8x Fuel Injectors For 2004-2010 Chevy GMC 4.8 5.3 6.0 6.2 12580681?

This product is a full set of eight new fuel injectors engineered to replace OEM part number 12580681. Specifically designed for General Motors 4.8L, 5.3L, 6.0L, and 6.2L V8 engines, these injectors are compatible with a wide range of Chevrolet and GMC vehicles from 2004 to 2010, including Silverado, Sierra, Tahoe, Yukon, Avalanche, and Suburban models. Sold by Lab Work Auto, this set offers a cost-effective solution for restoring engine efficiency, improving fuel economy, and eliminating misfires or rough idling caused by worn injectors.

Key features

  • OEM Replacement — Matches factory specifications for 12580681 injectors.
  • Complete Set — Includes all 8 injectors needed for V8 engine replacement.
  • Broad Fitment — Compatible with Chevrolet and GMC trucks, SUVs, and vans from 2004–2010.
  • Direct Fit — No modifications required; installs using standard tools.
  • Improved Performance — Restores fuel atomization, throttle response, and engine smoothness.
  • Affordable Upgrade — High-value set priced at just $43.95.

Who is New 8x Fuel Injectors For 2004-2010 Chevy GMC 4.8 5.3 6.0 6.2 12580681 for?

This set is ideal for DIY mechanics and auto repair shops servicing GM V8-powered vehicles. It’s especially useful for owners of high-mileage trucks or SUVs experiencing fuel delivery issues, reduced power, or check engine lights related to injector performance. Whether rebuilding an engine or performing preventative maintenance, this kit provides a reliable, factory-spec solution without the dealership price tag.

How does New 8x Fuel Injectors For 2004-2010 Chevy GMC 4.8 5.3 6.0 6.2 12580681 compare?

Compared to individual injector replacements or remanufactured sets, this new 8-pack offers better value and consistency across all cylinders. Unlike generic or off-brand injectors, it’s built to match OEM 12580681 specs for reliable fit and function. While performance-tuned injectors exist for modified engines, this set is optimized for stock or near-stock applications where reliability and fuel economy matter most.

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Best use cases

  • Replacing worn fuel injectors
  • Engine rebuilds on GM V8s
  • Fixing misfires or rough idle
  • Improving fuel efficiency
  • Preventative maintenance
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Is New 8x Fuel Injectors For 2004-2010 Chevy GMC 4.8 5.3 6.0 6.2 12580681 right for you?

This injector set is best for DIYers and mechanics maintaining 2004–2010 GM trucks and SUVs with V8 engines. Basic mechanical skills and standard tools are sufficient for installation. If your vehicle has performance mods or needs high-flow injectors, consider upgraded options. For stock engines, this set delivers reliable, factory-matched performance at a fraction of dealer prices.

How it compares: Compared to remanufactured or single-unit replacements, this new set offers better consistency and value. It matches OEM specs unlike generic brands, and costs less than dealer parts while delivering similar reliability for stock engine applications.

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Frequently Asked Questions

What vehicles are compatible with these fuel injectors?

These injectors fit 2004–2010 Chevrolet and GMC trucks and SUVs with 4.8L, 5.3L, 6.0L, and 6.2L V8 engines, including Silverado, Sierra, Tahoe, Yukon, Avalanche, and Suburban models.

Does this set require programming or calibration?

No, these are direct OEM-replacement injectors that do not require coding or calibration. They install and function like factory units using your vehicle’s existing ECU settings.

How do fuel injectors improve engine performance?

Fresh injectors restore precise fuel delivery, improving combustion efficiency. This enhances power, smoothness, fuel economy, and reduces emissions caused by clogged or leaking old injectors.

Is this set new or remanufactured?

This is a brand-new set of eight fuel injectors, not rebuilt or remanufactured. They are built to match OEM 12580681 specifications for reliable performance and fitment.

Can I install these injectors myself?

Yes, if you have basic mechanical experience and tools. Replacing fuel injectors involves removing the intake manifold on most LS engines, so intermediate DIY skills are recommended.

How much does New 8x Fuel Injectors For 2004-2010 Chevy GMC 4.8 5.3 6.0 6.2 12580681 cost?

New 8x Fuel Injectors For 2004-2010 Chevy GMC 4.8 5.3 6.0 6.2 12580681 is $43.95 at Lab Work Auto. Prices may change — click through to Lab Work Auto for the latest.

Is New 8x Fuel Injectors For 2004-2010 Chevy GMC 4.8 5.3 6.0 6.2 12580681 in stock at Lab Work Auto?

Yes, New 8x Fuel Injectors For 2004-2010 Chevy GMC 4.8 5.3 6.0 6.2 12580681 is currently in stock at Lab Work Auto.

Specifications

SKU
F7-6371
Last updated May 14, 2026