Melanocyl Ointment (Methoxsalen 0.75% w/w + Aminobenzoic Acid 2% w/w)

What is Melanocyl Ointment (Methoxsalen 0.75% w/w + Aminobenzoic Acid 2% w/w)?

Melanocyl Ointment is a compounded topical medication containing Methoxsalen (0.75% w/w) and Aminobenzoic Acid (2% w/w), used primarily as a photosensitizing agent in the treatment of vitiligo. Methoxsalen, a psoralen derivative, enhances skin sensitivity to ultraviolet A (UVA) light, promoting melanocyte activation and pigment restoration. Aminobenzoic Acid may support skin health and act as a protective antioxidant. The ointment is applied externally to depigmented areas before controlled UVA or sunlight exposure as part of a phototherapy regimen.

Key features

• Active Dual-Action Formula — Combines Methoxsalen and Aminobenzoic Acid to stimulate melanin production.
• Topical Application — Targeted treatment for localized vitiligo patches.
• Photosensitizing Agent — Enhances skin response to UV light therapy.
• Prescription-Based — Requires medical supervision for safe use.
• Non-Invasive Option — Alternative to oral psoralens with potentially reduced systemic effects.
• Stable Ointment Base — Designed for consistent delivery and skin penetration.
• Used in PUVA Therapy — Integral in topical photochemotherapy protocols.

Who is Melanocyl Ointment (Methoxsalen 0.75% w/w + Aminobenzoic Acid 2% w/w) for?

This ointment is intended for individuals diagnosed with vitiligo, especially those with localized or segmental depigmentation. It is best suited for patients undergoing dermatologist-supervised phototherapy. Not recommended for widespread use without medical guidance due to photosensitivity risks. Ideal for patients seeking targeted repigmentation with minimal systemic absorption.

How does Melanocyl Ointment (Methoxsalen 0.75% w/w + Aminobenzoic Acid 2% w/w) compare?

Compared to oral psoralen treatments, Melanocyl Ointment offers localized action with reduced risk of systemic side effects like nausea or liver strain. It differs from corticosteroid or calcineurin inhibitor creams by requiring UV exposure for efficacy. Unlike over-the-counter pigmentation products, it is a prescription-grade photosensitizer. When compared to standard polypropylene-based moisturizers or barrier creams, it serves a specific therapeutic role in repigmentation protocols rather than symptomatic relief.